Post Cycle Therapy PCT An Overview

As described previously, aromatase has also been found in a wide variety of tissues, including ovary, placenta, bone, adipose, testis, skin, and the brain 17, 21–25. However, only in primates has aromatase been shown to function in tissues other than the gonads or brain. In primates, tissue specific expression of aromatase is controlled by the presence of tissue specific promoters 25, 26. Aromatase is the only known vertebrate enzyme that can aromatize a six-membered ring; aromatase is, therefore, the sole source of estrogen in the body 27. Arimistane is an aromatase inhibitor that blocks the aromatase enzyme, so it can’t convert testosterone to estrogen. Since Arimistane can block this conversion process, it is helpful for both lowering estrogen and keeping it at the low level it needs to be in males.

HCG (Human Chorionic Gonadotropin) is taken by a lot of steroid users both on cycle and as part of PCT. But when you use HCG as one aspect of PCT, you’re providing a lot of extra support for endogenous testosterone function recovery. They can stimulate the release of more testosterone and result in a drop or shutdown of natural testosterone once you stop using them – just like anabolic steroids. Complete recovery of testosterone function is your number one goal of PCT. And that means using the optimal SERM dose to get you to the point where your natural testosterone is back to functioning as it was before your steroid cycle.

SARMs vs. SERMs: What’s the difference?

• There have even been studies comparing the effects of Arimidex and Letrozole (on women with breast cancer).
• Nevertheless, the benefit of AIs is often limited by the emergence of resistance.
• Some countries have very lenient laws, some allow over the counter purchases without a prescription and everything in between.
• Again, excessive estrogen levels can play havoc with both your sex drive and performance34.
• Arimistane is another aromatase inhibitor that stops testosterone from converting to estrogen, thus preventing the estrogenic side effects of anabolic steroid use.

Numerous large randomized studies are being conducted to address the value of these agents in the adjuvant setting. Additional information regarding the value of new aromatase inhibitors in combination with LHRH agonists will be available from studies in premenopausal women. All three third-generation aromatase inhibitors have also been compared with tamoxifen as first-line therapy for estrogen-receptor-positive or estrogen-receptor-unknown metastatic breast cancer in postmenopausal women.

Aromatase inhibitors

But your body still makes estrone, an estrogen created by converting a male sex hormone found in the adrenal glands, fat cells, and muscle. Although not technically considered a stack, Arimistane is often combined with other ingredients in fitness supplements. Many other ingredients are natural ingredients known or thought to positively impact testosterone, metabolism, muscle growth, and energy. Some of these natural ingredients with which Arimistane is often combined within supplements include fenugreek, tribulus terrestris, Mucuna Pruriens, and amino acids like L-Citrulline. 7-Keto-DHEA is used to increase metabolism and thermogenesis (body heat), mainly to aid in fat loss and build muscle. However, 7-Keto-DHEA is also a banned substance by world doping bodies.

Androgenic side effects

If you are prone to high cholesterol, then choosing a SERM for on-cycle estrogen level control rather than an AI like Arimidex can eliminate this problem for you. Arimidex can raise your cholesterol, which includes increasing LDL and total cholesterol. Studies on the long-term use of Arimidex showed this to be a problem6. However, at the same time, the patients recorded increased HDL (good) cholesterol levels.

If you are looking for an AI for your testosterone needs, such as in the protection against estrogenic side effects, which can Halotestin be useful in some low testosterone treatment plans, you are encouraged to visit Lowtestosterone.com. While providing a wide selection of high-quality products at affordable prices, we strongly emphasize client anonymity and ensure your personal information remains secure. Looking at the side effects of Aromasin, along with those of other common bodybuilding steroids, it’s not hard to see why the natural option can be worth a try if you want to save yourself from countless health nightmares. During clinical trials, subjects were reporting musculoskeletal pain when receiving a treatment of Aromasin. And it wasn’t just one study; multiple studies have confirmed that the use of Aromasin might result in random pain throughout the body.